糖心破解版

Einstein Study of How Genes Activate Shows Certain Genes are "Clueless" Scientists at  of 糖心破解版 have made an unexpected finding about the method by which certain genes are activated. Contrary to what researchers have traditionally assumed, genes that work with other genes to build protein structures do not act in a coordinated way but instead are turned on randomly. The surprising discovery, described in the December 5 online edition of Nature Structural and Molecular Biology, may fundamentally change the way scientists think about the way cellular processes are synchronized. httpv:// All cells contain protein complexes that perform essential functions, such as producing energy and helping cells divide. Assembling these multi-protein structures requires many different genes, each of which codes for one of the proteins that, collectively, form what鈥檚 known as the protein complex. Ribosomes, for example, are the vitally important structures on which proteins are synthesized. (The ribosomes of humans and most other organisms are composed of ribonucleic acid (RNA) and 80 different proteins.) Scientists have long assumed that genes involved in making such complex structures are activated in a highly-coordinated way. 鈥淲hat we found was rather astonishing,鈥� said , professor and co-chair of , professor of  and of  at Einstein and senior author of the study. 鈥淭he expression of the genes that make the protein subunits of ribosomes and other multi-protein complexes is not at all coordinated or co-regulated. In fact, such genes are so out of touch with each other that we dubbed them 鈥渃lueless鈥� genes.鈥�